Professional Profile

Robert C. Speth, B.A., M.A., Ph.D.

Photo Professor
Dept: Pharmaceutical Sciences
Phone: 954-262-1330
Email: rs1251@nova.edu
Campus: Fort Lauderdale

Biosketch:
Robert C. Speth, B.A., M.A., Ph.D. Professor Dept: Pharmaceutical Sciences Phone: 954-262-1330 Email: rs1251@nova.edu Campus: Fort Lauderdale EDUCATION/TRAINING: Western Maryland College, Westminster, MD, B.A.Biology, Psychology; Connecticut College, New London, CT, M.A. 1972 Physiological Psychology; Vanderbilt University, Nashville, TN, Ph.D. 1976 Pharmacology; Univ. Arizona, Tucson, AZ (H.I. Yamamura) Post-Doc. 1976-9 Pharmacology SELECTED POSITIONS AND HONORS: NRSA Post-Doctoral Fellow 1978; Adjunct Asst. Professor, Dept. Pharmacology, Univ.Arizona School of Medicine, Tucson, AZ 1979; Associate Staff, Cleveland Clinic, Cleveland, OH 1979-1984; Associate/Full Professor/Graduate Faculty: Department of Vet. Comp. Anat., Pharmacol. Physiol. (VCAPP), Pharmacology/Toxicology and Neuroscience Programs, Washington State Univ., Pullman, WA 1984-2003; Director, Peptide Radioiodination Service Center: Washington State University, Pullman, WA, Univ Mississippi, 1991-2009; Fellow, AAAS 1996; 1999-2000 Visiting Scientist, Oregon Health Sciences University, Beaverton, OR 1999-2000; Chair/Professor, Dept. Pharmacology, School of Pharmacy, Univ.Mississippi, University MS 2003-2009; Professor of Pharmaceutical Sciences, College of Pharmacy, Nova Southeastern Univ, Fort Lauderdale, FL 2009-present; Courtesy Professor, Dept. Physiology and Functional Genomics, Univ. Florida, Gainesville, FL 2012-present; Adjunct Professor of Pharmacology and, College of Medicine, Georgetown Univ. Washington, DC 2013-present. Awards: Lewis J. Kettle Award: Incurably Ill for Animal Research (October 1998); Dr. T.S. Williams Lecturer Award: Tuskegee Veterinary Medical Alumni Assoc. (March 1998); Washington State Univ. Faculty Library Awards Washington State Univ. (April 1999, June 2003) Keynote Speaker Tri-Beta Induction Ceremony Farquhar College of Arts and Sciences, Nova Southeastern University April 10, 2014. PERSONAL STATEMENT: The career goals I pursue are to make meaningful contributions to the body of scientific knowledge applicable to human health and to teach and train students and fellows to continue this quest. I teach Bioethics and Pharmacology, with emphasis on Neuro and cardiovascular pharmacology. My research studies the pathophysiological mechanisms by which the renin-angiotensin system (RAS) affects the body. An additional focus of my research is the development and application of radioligands for use in receptor and enzyme binding studies. Notable discoveries include the first report of AT1 and AT2 receptor subtype distribution in the brain, providing the radioligand and cultured cells used to clone the AT2 receptor, the first receptor autoradiography of the AT4 receptor subtype, characterization of the mas protein as the angiotensin (1-7) receptor, and identifying the enzyme neurolysin as an additional binding site for angiotensin peptides. Currently my lab studies enzymes of the metabolic pathways of the RAS and involvement of the RAS in cognitive function. I have coauthored more than 180 peer-reviewed scientific articles that can be accessed at www.pubmed.gov by searching for Speth R. In addition, I have academic interests in the subject of misrepresentation and misuse of dietary supplements and drugs, advocating for the humane use of animals in biomedical research and other animal enterprises, and the integration of arts into the sciences.
 
Research Interests:
Receptor pharmacology, Neuroscience, regulation of the cardiovascular system, radioligand binding, receptor autoradiography, renin-angiotensin system, biased agonism behavior of G protein coupled receptors
Research Interests keywords:
Brain, Central Nervous System, Pharmacology, Receptors, Radioligands, Renin-Angiotensin System, Receptor autoradiography, Radioligand binding assays, Hypertension, Cardiovascular disease, immunohistochemistry

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